321

n. Used to describe someone who is retarded, moronic, stupid, inept, etc.
Derived from the disorder Trisomy 21, which is the cause for down syndrome. A handy phrase to use in public when you want to call something retarded, but the non-politically correct nature of the word doesn't allow you to do so.

An insult similar to "fucken retard"
three-twentyone is the genetic code for Down Syndrome, a genetic disorder, a common form of retardation

Originating in Mankato Minnesota, Matt R was credited with the term. The term refers to nutting on someones face. While the word is known by only locals, "321 Up On It" has been found being used in day to day conversations.

321's ; means the runs, dyorea.

If a song exists this rule states there also exists a dubstep remix of it